Search results for "MICROSATELLITE POLYMORPHISM"
showing 2 items of 2 documents
Chimerism and genetic diversity within the cultivar group of pinots
2002
Three clones of Vitis vinifera cv. pinot gris were analysed at 50 microsatellite loci to assess the presence of intra-varietal genetic variability. Two clones revealed a polymorphism expressed by the presence of three alleles at 5 loci instead of the two expected for a diploid species. By sequencing the three alleles amplified at two loci, we confirm that they correspond to different allelic states of the same locus but differ in their number of repeat units. Such tri-allelic profiles could reveal periclinal chimeras in which the two cell layers of the apical meristem are genetically different. For two clones, this periclinal chimeric state has been deduced from the comparison of the genoty…
Association of interleukin-10G microsatellite polymorphism with the susceptibility of ankylosing spondylitis
2013
Study suggests an association of IL10.G poly- morphisms with AS which might contribute to the increased or decreased susceptibility to AS. IL10.G8 and G7 microsatellites alleles appear as protective alleles against the development of AS in the German subjects investigated here. Allele IL10.G9 seems to be a risk factor for the development of AS. This protective effect of variant promoter alleles could be related to differences in IL- 10 production, which may be clinically relevant.